Basic Information |
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| Product Name： | ZIDOVUDINE |
| CAS： | 30516-87-1 ;146426-54-2 ;162537-11-3 |
| English Synonyms： | 1-[(2R,4S,5S)-4-AZIDO-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE ; RETROVIR ; 3-AZIDO-1,2,3-TRIDEOXY-1-(3,4-DIHYDRO-5-METHYL-2,4-DIOXO-1(2H)-PYRIMIDINYL)-D-ERYTHRO-PENTOFURANURONIC ACID ; AZT ; 1-((2R,4S,5S)-4-AZIDO-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-5-METHYL-1H-PYRIMIDINE-2,4-DIONE ; 1-((3S,4R)-4-(METHYLTHIO)TETRAHYDROFURAN-3-YL)PIPERAZINE ; ZDV ; TIMAZID ; 3′-AZIDO-3′-DEOXYTHYMIDINE ; 3'-AZIDO-3'-DEOXYTHYMIDINE ; 3'-AZIDO-2',3'-DIDEOXYTHYMIDINE ; AZIDOTHYMIDINE ; 1-((2R,4S,5S)-4-AZIDO-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE ; 1-(3-AZIDO-2,3-DIDEOXY-BETA-D-RIBOFURANOSYL)-5-METHYLPYRIMIDINE-2,4-(1H,3H)-DIONE ; ZIDOVUDINE ; RETROVIS |
| MDL Number.： | MFCD00006536 |
| H bond acceptor： | 9 |
| H bond donor： | 2 |
| Smile： | Cc1cn(c(=O)[nH]c1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-] |
| InChi： | InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1 |
| InChiKey： | InChIKey=HBOMLICNUCNMMY-XLPZGREQSA-N |
Property |
|
| Melting Point： | 113-115 DEG C(LIT) |
| Comments： | ASSAY METHOD: HPLC BIOCHEM/PHYSIOL ACTIONS: REVERSE TRANSCRIPTASE INHIBITOR ACTIVE AGAINST HIV-1 VIRUS OTHER NOTES: A POTENT, SELECTIVE INHIBITOR OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION IN MT-4 AND ATH8 CELLS RTECS: XP2072000 SOLUBILITY: H2O: SOLUBLE 50 MG/ML, CLEAR, COLORLESS TO SLIGHTLY YELLOW STORAGE TEMPERATURE: -20 DEG C TOTAL IMPURITIES: UNSPSC: 12352200 WGK: 3 |
Safety information |
|
| Symbol： |
GHS08
|
| Signal word： | Warning |
| Hazard statements： | H351 |
| Precautionary statements： | P281 |
| hazard symbol： | Xn |
| Risk Code： | R:40 |
| Safe Code： | S:36/37/39-45 |
| WGK Germany： | 3 |
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