FOSFOMYCIN SODIUM ,26016-99-9 _Chemical Cloud Database

FOSFOMYCIN SODIUM

Basic Information
Product Name：	FOSFOMYCIN SODIUM
CAS：	26016-99-9 ;4719-75-9
English Synonyms：	FOM-NA ; FOSFOMYCIN ; TETRASODIUM FOSFESTROL ; (1R,2S)(-)-(1,2-EPOXYPROPYL) PHOSPHONIC ACID DISODIUM SALT ; FOSFOMYCIN DISODIUM SALT ; DISODIUM PHOSPHONOMYCIN ; DISODIUM FOSFOMYCIN ; PHOSPHONOMYCIN ; FOSFOMYCIN SODIUM ; DISODIUM (1R,2S)-(1,2-EPOXYPROPYL)PHOSPHONATE ; (2R-CIS)-(3-METHYLOXIRANYL) PHOSPHONIC ACID DISODIUM SALT ; PHOSPHONOMYCIN DISODIUM SALT ; FOSFOMYCIN DISODIUM ; (-)-(1R,2S)-(1,2-EPOXYPROPYL)PHOSPHONIC ACID DISODIUM SALT ; PHOSPHOMYCIN DISODIUM SALT
MDL Number.：	MFCD00056853
H bond acceptor：	4
H bond donor：	0
Smile：	C[C@@H]1[C@@H](O1)P(=O)([O-])[O-].[Na+].[Na+]
InChi：	InChI=1S/C3H7O4P.2Na/c1-2-3(7-2)8(4,5)6;;/h2-3H,1H3,(H2,4,5,6);;/q;2*+1/p-2/t2-,3+;;/m1../s1
InChiKey：	InChIKey=QZIQJIKUVJMTDG-OTUWWBTESA-L
Property
Comments：	BIOCHEM/PHYSIOL ACTIONS: ANTIBIOTIC THAT CONCENTRATES IN KIDNEY AND BLADDER BIOCHEM/PHYSIOL ACTIONS: REDUCES NEPHROTOXICITY AND OTOTOXICITY OF PLATINUM-CONTAINING ANTI-TUMOR AGENTS. FOSFOMYCIN IS A PHOSPHOENOLPYRUVATE ANALOG THAT IRREVERSIBLY INHIBITS UDP-GLCNAC ENOLPYRUVYL TRANFERASE (MURA), AN ENZYME INVOLVED IN BACTERIAL CELL WALL BIOSYNTHESIS. AS A RESULT, THE PRODUCTION OF N-ACETYLMURAMIC ACID, AN ESSENTIAL ELEMENT OF THE PEPTIDOGLYCAN CELL WALL, IS INHIBITED LEGAL INFORMATION: VETRANAL IS A TRADEMARK OF SIGMA-ALDRICH CO LLC WGK: 3
Specification：	VETRANAL(TM)
Safety information

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