Basic Information |
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| Product Name： | TAMOXIFEN CITRATE |
| CAS： | 10540-29-1 ;54965-24-1 |
| English Synonyms： | TAMOXIFEN DRUG STANDARD SOLUTION ; (Z)-2-[4-(1,2-DIPHENYL-1-BUTENYL)PHENOXY]-N,N-DIMETHYLETHANAMINE CITRATE ; NOLVADEX ; (Z)-1-(P-DIMETHYLAMINOETHOXYPHENYL)-1,2-DIPHENYL-1-BUTENE CITRATE SALT ; (Z)-1-(P-DIMETHYLAMINOETHOXYPHENYL)-1,2-DIPHENYL-1-BUTENE CITRATE ; ZYNOPLEX ; TAMOFEN ; TAMOXIFEN (CITRATE) ; (2-(4-[(1Z)-1,2-DIPHENYLBUT-1-EN-1-YL]PHENOXY)ETHYL)DIMETHYLAMINE, 2-HYDROXYPROPANE-1,2,3-TRICARBOXYLIC ACID ; VALODEX ; TAMOXIFEN ; CIS-1-(4-DIMETHYLAMINOETHOXYPHENYL)-1,2-DIPHENYL-1-BUTENE CITRATE ; NOLTAM ; TAMOXIFENCITRATE ; Z-TAMOXIFEN CITRATE ; ISTUBAL ; TERIMON ; (Z)-2-(4-(1,2-DIPHENYL-1-BUTENYL)PHENOXYL)-N,N-DIMETHYL-ETHANAMINE-CITRATE ; TAMOXIFEN CITRATE SALT ; TAMOXASTA ; (Z)-1-(4-DIMETHYLAMINOETHOXYPHENYL)-1,2-DIPHENYL-1-BUTENE CITRATE ; KESSAR ; ETHANAMINE, 2-[4-[(1Z)-1,2-DIPHENYL-1-BUTENYL]PHENOXY]-N,N-DIMETHYL-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1) SALT ; TAMOXIFEN CITRATE ; (2-[4-(1,2-DIPHENYL-1-BUTEN-1-YL)PHENOXY]ETHYL)DIMETHYLAMINE 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE SALT |
| MDL Number.： | MFCD00058321 |
| H bond acceptor： | 2 |
| H bond donor： | 0 |
| Smile： | CC/C(=C(\c1ccccc1)/c2ccc(cc2)OCCN(C)C)/c3ccccc3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
| InChi： | InChI=1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-; |
| InChiKey： | InChIKey=FQZYTYWMLGAPFJ-OQKDUQJOSA-N |
Property |
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| Melting Point： | 140-144 °C |
| Comments： | BIOCHEM/PHYSIOL ACTIONS: PROTEIN KINASE C INHIBITOR. INDUCES APOPTOSIS IN HUMAN MALIGNANT GLIOMA CELL LINES. TAMOXIFEN AND ITS METABOLITE 4-HYDROXYTAMOXIFEN ARE SELECTIVE ESTROGEN RESPONSE MODIFIERS (SERMS) THAT ACT AS ESTROGEN ANTAGONISTS IN MAMMARY GLAND. BLOCKS ESTRADIOL-STIMULATED VEGF PRODUCTION IN BREAST TUMOR CELLS FOR PERFORMANCE TEST GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
Safety information |
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| Symbol： |
GHS07
GHS08
|
| Signal word： | Danger |
| Hazard statements： | H302-H350-H360 |
| Precautionary statements： | P201-P308 + P313 |
| hazard symbol： | T |
| Risk Code： | R:45-60-61-22-64 |
| Safe Code： | S:36/37/39-45 |
| WGK Germany： | 3 |
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