L-BUTHIONINE-(S,R)-SULFOXIMINE ,83730-53-4

L-BUTHIONINE-(S,R)-SULFOXIMINE

Basic Information
Product Name：	L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS：	83730-53-4
English Synonyms：	L-BUTHIONINE-SULFOXIMINE ; (2S)-2-AMINO-4-(S-BUTYLSULFONIMIDOYL)BUTANOIC ACID ; (2S)-2-AMINO-4-(BUTYLSULFONIMIDOYL)BUTANOIC ACID ; L-BUTHIONINE-(S,R)-SULFOXIMINE ; L-BSO ; BUTHIONINE SULFOXIMINE
MDL Number.：	MFCD00067000
H bond acceptor：	5
H bond donor：	3
Smile：	CCCCS(=N)(=O)CC[C@@H](C(=O)O)N
InChi：	InChI=1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12)/t7-,14?/m0/s1
InChiKey：	InChIKey=KJQFBVYMGADDTQ-CVSPRKDYSA-N
Property
Melting Point：	224-228 DEG C (DEC)/234-235 °C
Comments：	APPLICATION: USED TO INDUCE EXPERIMENTAL GLUTATHIONE DEFICIENCY, TO INVESTIGATE ROLES OF GLUTATHIONE IN CELLULAR PROCESSES ASSAY METHOD: TLC BIOCHEM/PHYSIOL ACTIONS: BLOCKS CELLULAR RESISTANCE TO CHEMOTHERAPY BY INHIBITING GAMMA-GLUTAMYLCYSTEINE SYNTHETASE, A KEY ENZYME IN GLUTATHIONE BIOSYNTHESIS. USED TO INDUCE EXPERIMENTAL GLUTATHIONE DEFICIENCY, TO INVESTIGATE ROLES OF GLUTATHIONE IN CELLULAR PROCESSES OPTICAL ACTIVITY: [ALPHA]20/D +33+/-1 DEG, C = 1% IN 1 M HCL OTHER NOTES: POTENT SPECIFIC INHIBITOR OF GAMMA-GLUTAMYLCYSTEINE SYNTHETASE RTECS: EK7713440 SOLUBILITY: H2O: SOLUBLE 50 MG/ML, CLEAR, COLORLESS TO FAINTLY YELLOW STORAGE TEMPERATURE: 2-8 DEG C WGK: 3
Safety information
Risk Code：	R:R36/37/38;
Safe Code：	S:S26;S37/39/;
WGK Germany：	3

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