Basic Information |
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| Product Name： | DOXORUBICIN HYDROCHLORIDE |
| CAS： | 25316-40-9 ;23214-92-8 |
| English Synonyms： | ADRIAMYCIN HCL ; ADRIBLASTINA ; DOXORUBICIN HCL ; ADRIBLASTINA HYDROCHLORIDE ; DOXORUBICIN HYDROCHLORIDE ; ADRIAMYCIN HYDROCHLORIDE ; ADRIAMYCIN ; ADRIAMYCIN(DOXORUBICIN)/ ; CAELYX HYDROCHLORIDE ; DOXORUBICIN (HYDROCHLORIDE) ; DOXORUBICIN ; 5,12-NAPHTHACENEDIONE, 10-[(3-AMINO-2,3,6-TRIDEOXY-A-L-LYXO-HEXOPYRANOSYL)OXY]-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(2-HYDROXYACETYL)-1-METHOXY-, HYDROCHLORIDE (1:1), (8S,10S)- ; DOX HYDROCHLORIDE ; (1S,3S)-3-GLYCOLOYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL-(3-AMINO-2,3,6-TRIDESOXY-ALPHA-L-LYXO-HEXOPYRANOSID) HYDROCHLORIDE ; RUBEX HYDROCHLORIDE ; ADRIACIN HYDROCHLORIDE ; HYDROXYDAUNORUBICIN HYDROCHLORIDE ; DOXORUBICINE HCL ; DOX ; DOXORUBICIN HYDROCHLORIDE, 99% ; 14-HYDROXYDAUNOMYCIN HCL ; DOXORUBCIN HYDROCHLORIDE ; DOXORUBICIN(ADRIAMYCIN) HYDROCHLORIDE ; 14-HYDROXYDAUNOMYCIN HYDROCHLORIDE ; (8S,10S)-10-[(3-AMINO-2,3,6-TRIDEOXY-ALPHA-LYXO-HEXOPYRANOSYL)OXY]-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-5,12-NAPHTHACENEDIONE HYDROCHLORIDE ; DOXORUBICIN HCL SALT ; NSC 123127 HYDROCHLORIDE |
| MDL Number.： | MFCD00077757 |
| H bond acceptor： | 12 |
| H bond donor： | 6 |
| Smile： | C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](Cc3c2c(c4c(c3O)C(=O)c5cccc(c5C4=O)OC)O)(C(=O)CO)O)N)O.Cl |
| InChi： | InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1 |
| InChiKey： | InChIKey=MWWSFMDVAYGXBV-RUELKSSGSA-N |
Property |
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| Melting Point： | 216 DEG C (DEC)(LIT) |
| Comments： | BIOCHEM/PHYSIOL ACTIONS: ANTITUMOUR ANTIBIOTIC. EFFECT OF ADRIAMYCIN(R) ON HEART MITOCHONDRIAL DNA PROPERTIES BIOCHEM/PHYSIOL ACTIONS: IMMUNOSUPPRESSIVE AGENT BIOCHEM/PHYSIOL ACTIONS: INHIBITOR OF REVERSE TRANSCRIPTASE AND RNA POLYMERASE BIOCHEM/PHYSIOL ACTIONS: INTERCALATES IN DNA GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA LEGAL INFORMATION: ADRIAMYCIN IS A REGISTERED TRADEMARK OF RDF PHARMACIA AND UPJOHN S PA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
Safety information |
|
| Symbol： |
GHS07
GHS08
|
| Signal word： | Danger |
| Hazard statements： | H302-H315-H319-H350 |
| Precautionary statements： | P201-P305 + P351 + P338-P308 + P313 |
| hazard symbol： | T,Xi |
| Risk Code： | R:45-22-36/38 |
| Safe Code： | S:53-45 |
| WGK Germany： | 3 |
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