Basic Information |
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| Product Name： | TOBRAMYCIN |
| CAS： | 49842-07-1 ;32986-56-4 ;79645-27-5 |
| English Synonyms： | TOBRAMAXIN ; O-3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL-(1-4)-O-(2,6-DIAMINO-2,3,6-TRIDEOXY-ALPHA-D-RIBOHEXOPYRANOSYL-(1-4))-2-DEOXY-D-STREPTAMINE ; TOBRAMAX ; TOBRAMYCIN SULFATE ; NEBRAMYCIN FACTOR 6 ; NEBRAMYCIN VI ; NEBRAMYCIN 6 ; TOBREX ; OBRAMYCIN ; TOBRAMYCIN SULFATE ; GERNEBCIN ; TOBRAMYCIN ; (1S,2S,3R,4S,6R)-4,6-DIAMINO-3-[(2,6-DIAMINO-2,3,6-TRIDEOXY-ALPHA-D-RIBO-HEXOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 3-AMINO-3-DEOXY-ALPH ; TOBRADISTIN ; 6-O-(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)-2-DEOXY-4-O-(2,6-DIAMINO-2,3,6-TRIDEOXY-ALPHA-D-RIBO-HEXOPYRANOSYL)STREPTAMINE ; O-[3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL-(1->6)]-O-[2,6-DIAMINO-2,3,6-TRIDEOXY-ALPHA-D-RIBOHEXOPYRANOSYL-(1->4)]-2-DEOXY-D-STREPTAMINE ; NF 6 ; NEBRAMCYIN ; DISTOBRAM |
| MDL Number.： | MFCD00077885 |
| H bond acceptor： | 14 |
| H bond donor： | 10 |
| Smile： | C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H](C[C@@H]([C@H](O3)CN)O)N)N |
| InChi： | InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1 |
| InChiKey： | InChIKey=NLVFBUXFDBBNBW-PBSUHMDJSA-N |
Property |
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| Melting Point： | 178℃ |
| Comments： | PHARMACOPEIA TRACEABILITY: TRACEABLE TO BP 333 PHARMACOPEIA TRACEABILITY: TRACEABLE TO PHEUR T1500000 PHARMACOPEIA TRACEABILITY: TRACEABLE TO USP 1667508 WGK: 2 BIOCHEM/PHYSIOL ACTIONS: ELICITS MISCODING. SPECTRUM OF ACTIVITY: GRAM NEGATIVE BACTERIA. NOT EFFECTIVE AGAINST ENTEROCOCCI BIOCHEM/PHYSIOL ACTIONS: INHIBITS TRANSLOCATION BIOCHEM/PHYSIOL ACTIONS: TOBRAMYCIN IS AN AMINOGLYCOSIDE. MODE OF ACTION: BINDS TO 70S RIBOSOMAL SUBUNIT GENERAL DESCRIPTION: THIS CERTIFIED REFERENCE MATERIAL (CRM) IS PRODUCED AND CERTIFIED IN ACCORDANCE WITH ISO/IEC 17025 AND ISO GUIDE 34 OTHER NOTES: VALUES OF ANALYTES VARY LOT TO LOT |
Safety information |
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| WGK Germany： | 2 |
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