Basic Information |
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| Product Name： | E-64 |
| CAS： | 66701-25-5 |
| English Synonyms： | N-[N-(L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL]-L-LEUCYL)-AGMATINE ; TRANS-EPOXYSUCCINYL-LEUCYLAMIDO-[4-GUANIDINO]BUTANE ; L-TRANS-3-CARBOXYOXIRAN-2-CARBONYL-L-LEUCYLAGMATINE ; L-TRANS-EPOXYSUCCINYL-LEU-AGMATINE ; TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO(4-GUANIDINO)BUTANE ; E-64 ; E-64 PROTEASE INHIBITOR ; L-TRANS-EPOXYSUCCINYL-LEUCYLAMIDE-(4-GUANIDO)-BUTANE ; TRANS-EPOXYSUCCINYL-LEUCYLAMIDO-[4-GUANIDINO]BUTANE[L-3-TRANS-CARBOXY-OXIRAN-2-CARBONYL]-LEU-AGMATIN ; L-TRANS-EPOXYSUCCINYL-LEU-4-GUANIDINOBUTYLAMIDE ; EPOXYSUCCINYL-L-LEUCYLAMIDO-(4-GUANIDINO)BUTANE ; N-(TRANS-EPOXYSUCCINYL)-L-LEUCINE 4-GUANIDINOBUTYLAMIDE ; EXPOXY[L-3-TRANS-CARBOXYOXIRAN-2-CARBONYL]-L-LEU-AGMATIN ; REXOSTATINE ; N-[N-(L-3-TRANS-CARBOXIRANE-2-CARBONYL)-L-LEUCYL]-AGMATINE ; [L-3-TRANS-CARBOXY-OXIRAN-2-CARBONYL]-LEU-AGMATIN |
| MDL Number.： | MFCD00080261 |
| H bond acceptor： | 10 |
| H bond donor： | 6 |
| Smile： | CC(C)C[C@@H](C(=O)NCCCCNC(=N)N)NC(=O)[C@H]1[C@@H](O1)C(=O)O |
| InChi： | InChI=1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10+,11+/m0/s1 |
| InChiKey： | InChIKey=LTLYEAJONXGNFG-HBNTYKKESA-N |
Property |
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| Comments： | APPLICATION: E-64 IS AN EFFECTIVE LIGAND FOR AFFINITY PURIFICATION OF CYSTEINE PROTEASES. WHEN COUPLED TO A THIOLATED AFFINITY MATRIX, BINDING IS NO LONGER IRREVERSIBLE, BUT SPECIFICITY IS RETAINED ASSAY METHOD: TLC RTECS: RR0390000 SOLUBILITY: H2O: SOLUBLE 20 MG/ML, CLEAR, COLORLESS STORAGE TEMPERATURE: 2-8 DEG C UNSPSC: 12352200 WGK: 3 |
Safety information |
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| Safe Code： | S:S22;S24/25; |
| WGK Germany： | 3 |
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