Basic Information |
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| Product Name： | SPIRONOLACTONE |
| CAS： | 52-01-7 |
| English Synonyms： | 17-HYDROXY-7-ALPHA-MERCAPTO-3-OXO-17-ALPHA-PREGN-4-ENE-21-CARBOXYLIC ACID-GAMMA-LACTONE-7-ACETATE ; ALDACTONE ; 4,17ALPHA-PREGNEN-21-CARBOXYLIC ACID-17BETA-OL-3-ONE-7ALPHA-THIOL 21-17 GAMMA LACTONE 7-ACETATE ; 4-PREGNEN-21-OIC ACID-17ALPHA-OL-3-ONE-7ALPHA-THIOL GAMMA-LACTONE 7-ACETATE ; SPIRONOLACTONE ; ETHANETHIOIC ACID, S-[(7R,8R,9S,10R,13S,14S,17R)-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-HEXADECAHYDRO-10,13-DIMETHYL-3,5'-DIOXOSPIRO[17H-CYCLOPENTA[A]PHENANTHRENE-17,2'(3'H)-FURAN]-7-YL] ESTER ; ALDACTONE A ; VEROSPIRONE ; S-(10,13-DIMETHYL-3,5'-DIOXO-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-HEXADECAHYDRO-3'H-SPIRO[CYCLOPENTA[A]PHENANTHRENE-17,2'-FURAN]-7-YL) ETHANETHIOATE ; SPIRONE ; SPIROLANG ; 7ALPHA-(ACETYLTHIO)-17ALPHA-HYDROXY-3-OXOPREGN-4-ENE-21-CARBOXYLIC ACID GAMMA-LACTONE ; SPIRESIS ; SPIRIDON ; SPIROLACTONE ; URACTONE ; VEROSPIRON ; XENALON ; ACELAT ; (1'S,2R,2'R,9'R,10'R,11'S,15'S)-9'-(ACETYLSULFANYL)-2',15'-DIMETHYLSPIRO[OXOLANE-2,14'-TETRACYCLO[8.7.0.0(2,7).0(11,15)]HEPTADECAN]-6'-ENE-5,5'-DIONE |
| MDL Number.： | MFCD00082250 |
| H bond acceptor： | 4 |
| H bond donor： | 0 |
| Smile： | CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)CCC(=O)O5)C |
| InChi： | InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1 |
| InChiKey： | InChIKey=LXMSZDCAJNLERA-ZHYRCANASA-N |
Property |
|
| Melting Point： | 207-208 DEG C(LIT) |
| Comments： | BIOCHEM/PHYSIOL ACTIONS: SPIRONOLACTONE IS A COMPETITIVE ALDOSTERONE RECEPTOR ANTAGONIST. USED AS POTASSIUM SPARING DIURETIC GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
Safety information |
|
| Symbol： |
GHS08
|
| Signal word： | Danger |
| Hazard statements： | H360 |
| Precautionary statements： | P201-P308 + P313 |
| hazard symbol： | T |
| Risk Code： | R:60 |
| Safe Code： | S:53-22-36/37/39-45 |
| WGK Germany： | 3 |
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