Basic Information |
|
| Product Name： | CORTICOTROPIN |
| CAS： | 12279-41-3 ;53-06-5 ;16960-16-0 |
| English Synonyms： | ACTH (1-39), HUMAN ; ACTH(1-39) CORTICOTROPIN, HUMAN ; ACTH (1-39) ; CORTICOTROPIN TRIFLUOROACETATE ; CORTICOTROPIN A ; ACTH (1-39) TRIFLUOROACETATE (HUMAN) ; ADRENDCORTICOTROPHIC HORMONE ; ADRENOCORTICOTROPIC HORMONE ; CORTICOTROPHIN ; H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH ; ACTH ; CORTICOTROPIN ; TETRACOSACTIDE ACETATE ; ADRENOCORTICOTROPIC HORMONE (1-39), HUMAN ; ADRENOCORTICOTROPIC HORMONE FRAGMENT 1-39 ; ADRENOCORTICOTROPIC HORMONE HUMAN ; ADRENOCORTICOTROPIN ; ACETHROPAN ; ADRENOCORTICOTROPIC HORMONE (1-39) ; H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH ; SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF ; H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE-OH TRIFLUOROACETATE ; SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE |
| MDL Number.： | MFCD00145721 |
| H bond acceptor： | 0 |
| H bond donor： | 0 |
| InChi： | InChI=1S// |
| InChiKey： | InChIKey=MOSFIJXAXDLOML-UHFFFAOYSA-N |
Property |
|
| Comments： | ANTIBODY ADSORBANT: SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-GLY-LYS-LYS-ARG-ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE ASSAY METHOD: HPLC BIOCHEM/PHYSIOL ACTIONS: BESIDES THE PITUITARY, ACTH IS PRODUCED BY OTHER CELLS, INCLUDING MACROPHAGES. ACTH BINDS TO A SPECIFIC MEMBER OF THE MELANOCORTIN RECEPTOR FAMILY, THE MC2R, WHICH IS EXPRESSED IN OSTEOBLASTS, ESPECIALLY AT SITES OF ACTIVE BONE DEPOSITION. ACTH LIKELY HAS CONCENTRATION-DEPENDENT EFFECTS ON BONE METABOLISM IN VIVO OTHER NOTES: MULTIPLE FACTORS CONTROLLING ACTH SECRETION AT THE ANTERIOR PITUITARY LEVEL OTHER NOTES: PITUITARY HORMONE THAT STIMULATES GLUCOCORTICOID PRODUCTION. MOLECULAR MECHANISMS REGULATING ACTH SYNTHESIS AND RELEASE OTHER NOTES: REGULATION OF ADRENOCORTICOTROPIC HORMONE / BETA-LIPOTROPIC HORMONE RTECS: GM7900000 SOLUBILITY: H2O: SOLUBLE 1 MG/ML, CLEAR, COLORLESS STORAGE TEMPERATURE: -20 DEG C WGK: 3 |
Safety information |
|
| Symbol： |
GHS07
GHS08
|
| Signal word： | Warning |
| Hazard statements： | H302-H312-H332-H351 |
| Precautionary statements： | P280 |
| hazard symbol： | Xn |
| Risk Code： | R:20/21/22-40 |
| Safe Code： | S:22-36 |
| WGK Germany： | 3 |
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