Basic Information |
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| Product Name： | FLUCONAZOLE |
| CAS： | 86386-73-4 ;514222-44-7 |
| English Synonyms： | TRIFLUCAN ; 2,4-DIFLUORO-ALPHA,ALPHA-1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYLALCOHOL ; 2-(2,4-DIFLUOROPHENYL)-1,3-BIS(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL ; ALFUMET ; FLUCONAZOL ; FLUCONAZOLE, 98% ; TRICAN ; ALPHA-(2,4-DIFLUOROPHENYL)-ALPHA-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1H-1,2,4-TRIAZOLE-1-ETHANOL ; FLUCONAZOLE IMPURITY C ; FLUCONAZOLE ; 2-(2,4-DIFLUORO-PHENYL)-1,3-BIS-[1,2,4]TRIAZOL-1-YL-PROPAN-2-OL ; 2,4-DIFLUORO-,1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYL ALCOHOL ; DIFLUCAN ; 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL |
| MDL Number.： | MFCD00274549 |
| H bond acceptor： | 7 |
| H bond donor： | 1 |
| Smile： | c1cc(c(cc1F)F)C(Cn2cncn2)(Cn3cncn3)O |
| InChi： | InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2 |
| InChiKey： | InChIKey=RFHAOTPXVQNOHP-UHFFFAOYSA-N |
Property |
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| Comments： | BIOCHEM/PHYSIOL ACTIONS: FLUCONAZOLE IS AN ANTIFUNGAL AGENT. IT IS HIGHLY SELECTIVE INHIBITOR OF FUNGAL CYTOCHROME P-450 STEROL C-14 ALPHA-DEMETHYLLATION. FLUCONAZOLE IS A POTENT INHIBITOR OF CYP2C9. FLUCONAZOLE INTERFERES WITH FUNGAL ERGOSTEROL SYNTHESIS AND DOWNREGULATES THE METALLOTHIONEIN GENE FOR PEAK IDENTIFICATION GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
Safety information |
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| Symbol： |
GHS07
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| Signal word： | Warning |
| Hazard statements： | H302-H315-H319-H335 |
| Precautionary statements： | P261-P305 + P351 + P338 |
| hazard symbol： | Xn |
| Risk Code： | R:22-36/37/38 |
| Safe Code： | S:26-36 |
| WGK Germany： | 3 |
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