Basic Information |
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| Product Name： | GLIMEPIRIDE |
| CAS： | 93479-97-1 |
| English Synonyms： | GLISTA OD ; TRANS-1-(4-(2-(3-ETHYL-4-METHYL-2-OXO-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDO)ETHYL)PHENYLSULFONYL)-3-(4-METHYLCYCLOHEXYL)UREA ; 1-[[P-[2-(3-ETHYL-4-METHYL-2-OXO-3-PYRROLINE-1-CARBOXAMIDO)ETHYL]PHENYL]SULFONYL]-3-(TRANS-4-METHYLCYCLOHEXYL)UREA ; 3-ETHYL-4-METHYL-N-[2-(4-[[(TRANS-4-METHYLCYCLOHEXYL)CARBAMOYL]SULFAMOYL]PHENYL)ETHYL]-2-OXO-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE ; 3-ETHYL-4-METHYL-N-(4-(N-((1R,4R)-4-METHYLCYCLOHEXYLCARBAMOYL)SULFAMOYL)PHENETHYL)-2-OXO-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE ; GLIMY ; GLIMEPIRIDE, USP28 ; AMARYL ; GLIMPERIDE ; GLIMEPIRIDE ; 3-ETHYL-2,5-DIHYDRO-4-METHYL-N-[2-[4-[[[(TRANS-4-METHYLCYCLO-HEXYL)AMINO]CARBONYL]AMINO]SULFONYL]PHENYL]ETHYL-2-OXO-1H-PYRROLE-1-CARBOXAMIDE ; 3-ETHYL-4-METHYL-N-[2-[4-[(TRANS-4-METHYLCYCLOHEXYL) CARBAMOYLSULFAMOYL]PHENYL]ETHYL]-2-OXO-5H-PYRROL-1-CARBOXAMIDE |
| MDL Number.： | MFCD00878417 |
| H bond acceptor： | 9 |
| H bond donor： | 3 |
| Smile： | CCC1=C(CN(C1=O)C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@@H](CC3)C)C |
| InChi： | InChI=1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19- |
| InChiKey： | InChIKey=WIGIZIANZCJQQY-RUCARUNLSA-N |
Property |
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| Comments： | APPLICATION: GLIMEPIRIDE IS CURRENTLY USED TO TREAT TYPE 2 DIABETES BIOCHEM/PHYSIOL ACTIONS: GLIMEPIRIDE IS A POTENT BLOCKER OF CARDIAC KATP CHANNELS ACTIVATED BY PINACIDIL WITH AN IC50 OF 6.8 NM FOR SYSTEM SUITABILITY GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
Safety information |
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| WGK Germany： | 3 |
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