basic_info |
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| Product_Name： | AZITHROMYCIN DIHYDRATE |
| CAS： | 83905-01-5 ;117772-70-0 |
| EnglishSynonyms： | AZITHROMYCIN DIHYDRATE ; N-METHYL-11-AZA-10-DEOXO-10-DIHYDROERYTHROMYCIN A DIHYDRATE ; CP-62993 DIHYDRATE ; 9-DEOXO-9-METHYL-9ALPHA-AZA-9-HOMOERYTHROMYCIN A, DIHYDRATE ; AZITHROMYCIN 2H2O ; AZITHROMYCIN ; 9-DEOXO-9ALPHA-METHYL-9ALPHA-AZA-HOMOERYTHROMYCIN A, DIHYDRATE |
| pro_mdlNumber： | MFCD01862248 |
| pro_acceptors： | 14 |
| pro_donors： | 5 |
| pro_smile： | CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O.O.O |
| InChi： | InChI=1S/C38H72N2O12.2H2O/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28;;/h20-33,35,41-43,45-46H,15-19H2,1-14H3;2*1H2/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-;;/m1../s1 |
| InChiKey： | InChIKey=SRMPHJKQVUDLQE-KUJJYQHYSA-N |
property |
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| Comments： | BIOCHEM/PHYSIOL ACTIONS: AZITHROMYCIN DIHYDRATE IS A MACROLIDE ANTIBIOTIC, AZALIDE SUBCLASS. IT BINDS TO THE 50S SUBUNIT OF THE 70S BACTERIAL RIBOSOMES AND INHIBITS RNA-DEPENDENT PROTEIN SYNTHESIS IN BACTERIAL CELLS. AZITHROMYCIN ALSO HAS ANTI-IMMUNOMODULATORY/ANTI-INFLAMMATORY PROPERTIES, WHICH MAKE IT USEFUL IN TREATING CYSTIC FIBROSIS PHARMACOPEIA TRACEABILITY: TRACEABLE TO PHEUR Y0000306 PHARMACOPEIA TRACEABILITY: TRACEABLE TO USP 1046056 WGK: 3 |
secure_info |
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| secure_wgk_germany： | 3 |
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