Basic Information |
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| Product Name： | TFCS |
| CAS： | 117032-51-6 |
| English Synonyms： | 6-(N-TRIFLUOROACETYL)AMINOCAPROIC ACID N-SUCCINIMIDYL ESTER ; 6-(N-TRIFLUOROACETYL)CAPROIC ACID NHS ; TFCS ; 6-[(2,2,2-TRIFLUOROACETYL)AMINO]HEXANOIC ACID 2,5-DIOXO-1-PYRROLIDINYL ESTER ; N-[EPSILON-TRIFLUOROACETYLCAPROYLOXY]SUCCINIMIDE ESTER ; N-[6-[(2,5-DIOXO-1-PYRROLIDINYL)OXY]-6-OXOHEXYL]-2,2,2-TRIFLUORO-ACETAMIDE |
| MDL Number.： | MFCD01863466 |
| H bond acceptor： | 7 |
| H bond donor： | 1 |
| Smile： | C1CC(=O)N(C1=O)OC(=O)CCCCCNC(=O)C(F)(F)F |
| InChi： | InChI=1S/C12H15F3N2O5/c13-12(14,15)11(21)16-7-3-1-2-4-10(20)22-17-8(18)5-6-9(17)19/h1-7H2,(H,16,21) |
| InChiKey： | InChIKey=HROQVGGEVAAQOE-UHFFFAOYSA-N |
Property |
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| Comments： | AMINE-REACTIVE CROSS-LINKER WITH A LATENT AMINO GROUP AVAILABLE ON DEMAND FEATURES/BENEFITS: AMINE-REACTIVE MODIFICATION AGENT WITH A PROTECTED PRIMARY AMINE GROUP FEATURES/BENEFITS: NHS ESTER END COUPLES WITH PRIMARY AMINES AT PH 7-9 TO FORM STABLE AMIDE BONDS FEATURES/BENEFITS: NON-CLEAVABLE; WATER-INSOLUBLE FEATURES/BENEFITS: REACTIVE GROUPS: NHS ESTER AND TRIFLUOROACETYL-PROTECTED-NH2 FEATURES/BENEFITS: REACTIVE TOWARD: AMINO GROUPS AND NHS ESTERS/SULFO-NHS ESTERS OR EDC-ACTIVATED CARBOXYL GROUPS FEATURES/BENEFITS: TEMPORARILY BLOCK AMINE GROUPS IN TARGET MOLECULES FEATURES/BENEFITS: TRIFLUOROACETYL PROTECTING GROUP RELEASED BY PHOSPHATE OR BORATE BUFFER, PH 7.8-8.1 FEATURES/BENEFITS: UNMASKED AMINO GROUP READY FOR REACTION WITH ANY AMINE-REACTIVE CROSS-LINKER FOR CONJUGATE PREPARATION FEATURES/BENEFITS: USED TO EXTEND LYSINE SIDE-CHAIN LENGTH TO REDUCE STERIC HINDRANCE |
| Information： | SPACER ARM 7.7 ANGSTROM |
Safety information |
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