Basic Information |
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| Product Name： | S-100 ALPHA, BETA AND BETA, BETA HETERODIMER |
| English Synonyms： | S-100 ALPHA, BETA AND BETA, BETA HETERODIMER |
| MDL Number.： | MFCD03458421 |
| H bond acceptor： | 0 |
| H bond donor： | 0 |
| InChi： | InChI=1S// |
| InChiKey： | InChIKey=MOSFIJXAXDLOML-UHFFFAOYSA-N |
Property |
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| Comments： | APPLICATIONS: SUITABLE FOR USE AS A STANDARD IN IMMUNOASSAY, AS AN IMMUNOGEN FOR ANTISERUM PRODUCTION, AND TRACER FOR IODINATION ASSAY BY NATIVE ELECTROPHORESIS IN PRESENCE OF 2MM EGTA DESCRIPTION: APOPTOSIS AND SIGNAL TRANSDUCTION REAGENT, THE S-100 PROTEIN IS AN ACIDIC CALCIUM BINDING PROTEIN WITH THE MW OF APPROXIMATELY 21KDA DESCRIPTION: BECAUSE OF ITS PREDOMINANT LOCATION IN THE ASTROGLIAL CELLS, S-100 CAN BE USED AS A SENSITIVE AND RELIABLE MARKER FOR CENTRAL NERVOUS SYSTEM INJURY (CNS) DESCRIPTION: IN HUMAN BRAIN TISSUE, S-100 IS MAINLY PRESENTED BY TWO ISOFORMS: BETA, BETA HOMODIMER (S100B) AND ALPHA, BETA HETERODIMER (S-100A) DESCRIPTION: MEASUREMENTS OF S-100 IN PATIENT SERUM SAMPLES ARE USEFUL IN MONITORING TRAUMATIC BRAIN INJURY, ISCHEMIC BRAIN DAMAGE AFTER CIRCULATORY ARRESTS, AND IN DIAGNOSIS AND PROGNOSIS OF ACUTE STROKE DESCRIPTION: STRUCTRUAL DAMAGE OF GLIAL CELLS CAUSES LEAKAGE OF S-100 INTO THE EXTRACELLULAR MATRIX AND INTO CEREBROSPINAL FLUID, WITH RELEASE INTO THE BLOODSTREAM FORM: FREEZE-DRIED FROM DEIONIZED WATER WITH 5MM 2-MERCAPTOETHANOL AND 5MM EDTA FORM: IT IS RECOMMENDED TO RECONSTITUTE THE PRODUCT IN 5MM 2-MERCAPTOETHANOL SOLUTION MATERIAL SAFETY: ALL PRODUCTS ARE FOR RESEARCH OR MANUFACTURING PURPOSES ONLY, AND ARE NOT FOR USE IN HUMAN THERAPEUTIC PROCEDURES MATERIAL SAFETY: PROPER LABORATORY PROCEDURES SHOULD BE USED IN HANDLING RELATED DISCIPLINES: APOPTOSIS AND SIGNAL TRANSDUCTION SHIPPING CONDITIONS: BLUE ICE STORAGE CONDITIONS: -20 DEG C |
| Information： | SOURCE ORGANISM: HUMAN BRAIN TISSUE |
Safety information |
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