Basic Information |
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| Product Name： | CRYPTOTANSHINONE |
| CAS： | 4733-35-1 ;35825-57-1 |
| English Synonyms： | (R)-1,2,6,7,8,9-HEXAHYDRO-1,6,6-TRIMETHYL-PHENANTHRO(1,2-B)FURAN-10,11-DIONE ; CRYPTOTANSHINON ; (R)-1,6,6-TRIMETHYL-1,2,6,7,8,9-HEXAHYDROPHENANTHRO[1,2-B]FURAN-10,11-DIONE ; 1,2,6,7,8,9-HEXAHYDRO-1,6,6-TRIMETHYL-(R)-PHENANTHRO(1,2-B)FURAN-10,11-DIONE ; TANSHINONE C ; (R)-(-)-1,6,6-TRIMETHYL-1,2,6,7,8,9-HEXAHYDROPHENANTHRO[1,2-B]FURAN-10,11-DIONE ; TANSHINONE,CRYPTO ; CRYPTOTANSHINONE |
| MDL Number.： | MFCD07636810 |
| H bond acceptor： | 3 |
| H bond donor： | 0 |
| Smile： | C[C@H]1COC2=C1C(=O)C(=O)c3c2ccc4c3CCCC4(C)C |
| InChi： | InChI=1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1 |
| InChiKey： | InChIKey=GVKKJJOMQCNPGB-JTQLQIEISA-N |
Property |
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| Melting Point： | 184℃～185℃/184℃～185℃ |
| Comments： | ASSAY METHOD: HPLC BIOCHEM/PHYSIOL ACTIONS: CRYPTOTANSHINONE IS AN ANTIBACTERIAL AND ANTI-INFLAMMATORY COMPOUND ORIGINALLY EXTRACTED FROM THE ROOTS OF SALVIA MILTIORRHIAZ (DANSHEN). CRYPTOTANSHINONE HAS BEEN FOUND TO INHIBIT HIF ACTIVATION AND TO INHIBIT MACROPHAGE MIGRATION NEGATIVELY REGULATE THE PI3K PATHWAY. IT HAS DEMONSTRATED ACTIVITY AGAINST SEVERAL STRAINS OF STAPHYLOCOCCUS AUREUS OPTICAL ACTIVITY: [ALPHA]/D -85.0+/-3.0 DEG, C = 0.1 IN CHLOROFORM SHELF LIFE: LIMITED SHELF LIFE, EXPIRY DATE ON THE LABEL STORAGE TEMPERATURE: 2-8 DEG C WGK: 3 |
| Specification： | ANALYTICAL STANDARD |
Safety information |
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| Symbol： |
GHS06
GHS09
|
| Signal word： | Danger |
| Hazard statements： | H301-H410 |
| Precautionary statements： | P273-P301 + P310-P501 |
| hazard symbol： | T,N |
| Risk Code： | R:25-50/53 |
| Safe Code： | S:45-60-61 |
| WGK Germany： | 3 |
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