Basic Information |
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| Product Name： | CLINDAMYCIN HYDROCHLORIDE |
| CAS： | 18323-44-9 ;58207-19-5 ;21462-39-5 |
| English Synonyms： | CLINDOXYL ; CLINDAMYCIN (HYDROCHLORIDE) ; 7-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE ; BENZACLIN ; CLINDAMYCIN HCL (DALACIN) ; CLINDAMYCIN HYDROCHLORIDE ; CLINDAMYCIN ; CLINDAMYCIN HYDROCHLORIDE, BP EP USP ; CLEOCIN HYDROCHLORIDE ; CLINDAMYCIN HCL ; DALACIN ; 7[S]-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE ; (2S,4R)-N-((1S,2S)-2-CHLORO-1-((2R,3R,4S,5R,6R)-3,4,5-TRIHYDROXY-6-(METHYLTHIO)TETRAHYDRO-2H-PYRAN-2-YL)PROPYL)-1-METHYL-4-PROPYLPYRROLIDINE-2-CARBOXAMIDE HYDROCHLORIDE ; 7(S)-CHLORO-7-DEOXYLINCOMYCIN ; (7S)-7-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE ; U-21251F ; DUAC ; CLEOCIN |
| MDL Number.： | MFCD07793327 |
| H bond acceptor： | 7 |
| H bond donor： | 4 |
| Smile： | CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl.Cl |
| InChi： | InChI=1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1 |
| InChiKey： | InChIKey=AUODDLQVRAJAJM-XJQDNNTCSA-N |
Property |
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| Comments： | BIOCHEM/PHYSIOL ACTIONS: SPECTRUM OF ACTIVITY: GRAM POSITIVE COCCI AND TAXOPLASMA. ESPECIALLY ACTIVE AGAINST ANAEROBIC BACTERIA. MODE OF ACTION: INHIBITS PROTEIN SYNTHESIS IN BACTERIA BY BINDING THE 50S RIBOSOMAL SUBUNIT.CLINDAMYCIN IS A SEMI-SYNTHETIC, LINCOSAMIDE ANTIBIOTIC THAT IS PREPARED FROM LINCOMYCIN. IT INHIBITS BACTERIAL PROTEIN SYNTHESIS BY HYDROGEN BOND INTERACTIONS WITH THE 23S RRNA COMPONENT OF THE 50S RIBOSOMAL SUBUNIT THUS INDUCING DISSOCIATION OF THE PEPTIDYL-T-RNA COMPLEX. ANTIBACTERIAL AND ANTIPROTOZOAL ANTIBIOTIC GENERAL DESCRIPTION: THIS PRODUCT IS PROVIDED AS DELIVERED AND SPECIFIED BY THE ISSUING PHARMACOPOEIA. ALL INFORMATION PROVIDED IN SUPPORT OF THIS PRODUCT, INCLUDING MSDS AND ANY PRODUCT INFORMATION LEAFLETS HAVE BEEN DEVELOPED AND ISSUED UNDER THE AUTHORITY OF THE ISSUING PHARMACOPOEIA. FOR FURTHER INFORMATION AND SUPPORT PLEASE GO TO THE WEBSITE OF THE ISSUING PHARMACOPOEIA OTHER NOTES: ANTIBACTERIAL AND ANTIPROTOZOAL ANTIBIOTIC OF THE LICOSAMIDE CLASS OTHER NOTES: SALES RESTRICTIONS MAY APPLY |
Safety information |
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