SFAD ,220446-74-2 _Chemical Cloud Database

SFAD

Basic Information
Product Name：	SFAD
CAS：	220446-74-2
English Synonyms：	SFAD ; SULFOSUCCINIMIDYL-[PERFLUOROAZIDOBENZAMIDO]-ETHYL-1,3'-DITHIOPROPIONATE
MDL Number.：	MFCD12546446
H bond acceptor：	13
H bond donor：	1
Smile：	C1C(C(=O)N(C1=O)OC(=O)CCSSCCNC(=O)c2c(c(c(c(c2F)F)N=[N+]=N[Na])F)F)S(=O)(=O)[O-]
InChi：	InChI=1S/C16H13F4N5O8S3.Na/c17-10-9(11(18)13(20)14(12(10)19)23-24-21)15(28)22-2-4-35-34-3-1-8(27)33-25-7(26)5-6(16(25)29)36(30,31)32;/h6H,1-5H2,(H,22,28)(H,30,31,32);/q;+1/p-1
InChiKey：	InChIKey=LZWUCYAVMIKMIA-UHFFFAOYSA-M
Property
Comments：	FEATURES/BENEFITS: 19F NMR CAN BE USED TO MONITOR PERFLUOROARYL MOIETY TRANSFER FROM ONE PROTEIN TO ANOTHER FEATURES/BENEFITS: IMPROVED STABILITY OF THE SINGLET PERFLUOROARYL NITRENE REACTIVE INTERMEDIATE ALLOWS HIGH-EFFICIENCY INSERTION WITH -CH BONDS VS LOW EFFICIENCY RING EXPANSION WITH AMINE NUCLEOPHILES, TYPICAL OF NONFLUORINATED ARYL NITRENES FEATURES/BENEFITS: INSERTION EFFICIENCY APPROXIMATELY 70% FEATURES/BENEFITS: PERFLUOROPHENYL AZIDE MOIETY PHOTOLYZES AT 320 NM FEATURES/BENEFITS: REACTIVE GROUPS: SULFO-NHS ESTER AND PERFLUOROARYL AZIDE MOIETY FEATURES/BENEFITS: REACTIVE TOWARD: AMINO GROUPS AND -CH BONDS FEATURES/BENEFITS: WATER-SOLUBLE; CLEAVABLE SIGNIFICANTLY IMPROVED PHOTOCONJUGATION EFFICIENCY OVER TYPICAL ARYL AZIDE-CONTAINING CROSS-LINKERS
Information：	SPACER ARM 14.6 ANGSTROM
Safety information

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