EPZ015666

CAS No.
1616391-65-1
CCD No.
CCD08290762
Formula
C20H25N5O3
MolWeight
383.4442

Basic Information

Product Name: EPZ015666
CAS: 1616391-65-1
English Synonyms: (S)-N-(3-(3,4-DIHYDROISOQUINOLIN-2(1H)-YL)-2-HYDROXYPROPYL)-6-(OXETAN-3-YLAMINO)PYRIMIDINE-4-CARBOXAMIDE ; EPZ015666 ; EPZ-015666,EPZ 015666
H bond acceptor: 0
H bond donor: 0
Smile: C1N(CCC2=CC=CC=C12)C[C@H](CNC(=O)C1=NC=NC(=C1)NC1COC1)O
InChi: InChI=1S/C20H25N5O3/c26-17(10-25-6-5-14-3-1-2-4-15(14)9-25)8-21-20(27)18-7-19(23-13-22-18)24-16-11-28-12-16/h1-4,7,13,16-17,26H,5-6,8-12H2,(H,21,27)(H,22,23,24)/t17-/m0/s1
InChiKey: InChIKey=ZKXZLIFRWWKZRY-KRWDZBQOSA-N

Property

Information: EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5 nM, >20,000-fold selectivity over other PMTs.

Safety information

* If the product has intellectual property rights, a license granted is must or contact us.