SHP099 hydrochloride ,1801747-11-4 _Chemical Cloud Database

SHP099 hydrochloride

Basic Information
Product Name：	SHP099 hydrochloride
CAS：	1801747-11-4
English Synonyms：	6-(4-AMINO-4-METHYLPIPERIDIN-1-YL)-3-(2,3-DICHLOROPHENYL)PYRAZIN-2-AMINE HYDROCHLORIDE ; SHP099 HYDROCHLORIDE ; SHP099,SHP 099,SHP-099
H bond acceptor：	0
H bond donor：	0
Smile：	Cl.NC1(CCN(CC1)C1=CN=C(C(=N1)N)C1=C(C(=CC=C1)Cl)Cl)C
InChi：	InChI=1S/C16H19Cl2N5.ClH/c1-16(20)5-7-23(8-6-16)12-9-21-14(15(19)22-12)10-3-2-4-11(17)13(10)18;/h2-4,9H,5-8,20H2,1H3,(H2,19,22);1H
InChiKey：	InChIKey=KHQHYRFUYAXWOQ-UHFFFAOYSA-N
Property
Information：	SHP099 is a selective, orally bioavailable, and efficacious SHP2 inhibitor with IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM.
Safety information

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