Nazartinib(EGF816) ,1508250-71-2 _Chemical Cloud Database

Nazartinib(EGF816)

Basic Information
Product Name：	Nazartinib(EGF816)
CAS：	1508250-71-2
English Synonyms：	NAZARTINIB(EGF816) ; EGF-816
H bond acceptor：	0
H bond donor：	0
Smile：	ClC1=CC=CC2=C1N(C(=N2)NC(=O)C2=CC(=NC=C2)C)[C@H]2CN(CCCC2)C(\C=C\CN(C)C)=O
InChi：	InChI=1S/C26H31ClN6O2/c1-18-16-19(12-13-28-18)25(35)30-26-29-22-10-6-9-21(27)24(22)33(26)20-8-4-5-15-32(17-20)23(34)11-7-14-31(2)3/h6-7,9-13,16,20H,4-5,8,14-15,17H2,1-3H3,(H,29,30,35)/b11-7+/t20-/m1/s1
InChiKey：	InChIKey=IOMMMLWIABWRKL-WUTDNEBXSA-N
Property
Information：	Nazartinib(EGF816) is a novel covalent inhibitor of mutant-selective EGFR; overcomes T790M-mediated resistance in NSCLC.
Safety information

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