Basic Information |
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Product Name: | SAR020106 |
CAS: | 1184843-57-9 |
English Synonyms: | SAR 020106 ; SAR20106 ; SAR20106 ; SAR020106 ; SAR020106 ; SAR 20106 |
H bond acceptor: | 0 |
H bond donor: | 0 |
Smile: | ClC=1C=CC=C2C=C(N=CC12)NC=1N=C(C(=NC1)C#N)O[C@@H](CN(C)C)C |
InChi: | InChI=1S/C19H19ClN6O/c1-12(11-26(2)3)27-19-16(8-21)22-10-18(25-19)24-17-7-13-5-4-6-15(20)14(13)9-23-17/h4-7,9-10,12H,11H2,1-3H3,(H,23,24,25)/t12-/m1/s1 |
InChiKey: | InChIKey=SRBJWIBAMIKCMV-GFCCVEGCSA-N |
Property |
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Information: | SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC(50) of 13.3 nmol/L on the isolated human enzyme. |
Safety information |
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