AMG232 ,1352066-68-2 _Chemical Cloud Database

AMG232

Basic Information
Product Name：	AMG232
CAS：	1352066-68-2
English Synonyms：	AMG232 ; [(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-3- METHYL-1-[(2S)-3-METHYL-1-(PROPANE-2-SULFONYL)BUTAN-2-YL]-2-OXOPIPERIDIN-3-YL]ACETIC ACID ; AMG-232,AMG 232
H bond acceptor：	0
H bond donor：	0
Smile：	ClC=1C=C(C=CC1)[C@H]1C[C@](C(N([C@@H]1C1=CC=C(C=C1)Cl)[C@H](CS(=O)(=O)C(C)C)C(C)C)=O)(C)CC(=O)O
InChi：	InChI=1S/C28H35Cl2NO5S/c1-17(2)24(16-37(35,36)18(3)4)31-26(19-9-11-21(29)12-10-19)23(20-7-6-8-22(30)13-20)14-28(5,27(31)34)15-25(32)33/h6-13,17-18,23-24,26H,14-16H2,1-5H3,(H,32,33)/t23-,24-,26-,28-/m1/s1
InChiKey：	InChIKey=DRLCSJFKKILATL-YWCVFVGNSA-N
Property
Information：	AMG232 is a potent, selective and orally bioavailable inhibitor of MDM2?p53 interaction with IC50 value of 9.1 nM in EdU cells .
Safety information

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